BDBM50423729 CHEMBL611633::NCI-14893

SMILES: COc1cc(NC[C@](C)(O)N(CC(C)C)CC(C)C)c2nc(C)ccc2c1

InChI Key: InChIKey=DCLRNYUNFAFVPD-QFIPXVFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 6/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM50423729 (CHEMBL611633 | NCI-14893) Show SMILES COc1cc(NC[C@](C)(O)N(CC(C)C)CC(C)C)c2nc(C)ccc2c1 |r| Show InChI InChI=1S/C22H35N3O2/c1-15(2)12-25(13-16(3)4)22(6,26)14-23-20-11-19(27-7)10-18-9-8-17(5)24-21(18)20/h8-11,15-16,23,26H,12-14H2,1-7H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.91E+5	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Inhibition of CDK6/Cyclin D1 by FRET assay				Bioorg Med Chem Lett 20: 403-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.046 BindingDB Entry DOI: 10.7270/Q2GH9K7Q
					More data for this Ligand-Target Pair