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SMILES: Cc1nc2ccc3cnc(NC(=O)c4ccccc4)nc3c2s1

InChI Key: InChIKey=WFIWNOLZWKHKDY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50423771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50423771 (CHEMBL602746) Show SMILES Cc1nc2ccc3cnc(NC(=O)c4ccccc4)nc3c2s1 Show InChI InChI=1S/C17H12N4OS/c1-10-19-13-8-7-12-9-18-17(20-14(12)15(13)23-10)21-16(22)11-5-3-2-4-6-11/h2-9H,1H3,(H,18,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews Curated by ChEMBL					Assay Description inhibition of CDK1/Cyclin B				J Med Chem 53: 2136-45 (2010) Article DOI: 10.1021/jm901660c BindingDB Entry DOI: 10.7270/Q2377B0R
					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50423771 (CHEMBL602746) Show SMILES Cc1nc2ccc3cnc(NC(=O)c4ccccc4)nc3c2s1 Show InChI InChI=1S/C17H12N4OS/c1-10-19-13-8-7-12-9-18-17(20-14(12)15(13)23-10)21-16(22)11-5-3-2-4-6-11/h2-9H,1H3,(H,18,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews Curated by ChEMBL					Assay Description inhibition of CDK9/CyclinT1				J Med Chem 53: 2136-45 (2010) Article DOI: 10.1021/jm901660c BindingDB Entry DOI: 10.7270/Q2377B0R
					More data for this Ligand-Target Pair
Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50423771 (CHEMBL602746) Show SMILES Cc1nc2ccc3cnc(NC(=O)c4ccccc4)nc3c2s1 Show InChI InChI=1S/C17H12N4OS/c1-10-19-13-8-7-12-9-18-17(20-14(12)15(13)23-10)21-16(22)11-5-3-2-4-6-11/h2-9H,1H3,(H,18,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of St. Andrews Curated by ChEMBL					Assay Description inhibition of CDK7/Cyclin H/MAT1				J Med Chem 53: 2136-45 (2010) Article DOI: 10.1021/jm901660c BindingDB Entry DOI: 10.7270/Q2377B0R
					More data for this Ligand-Target Pair