BDBM50423870 CHEMBL2024147

SMILES: COc1ccc(cc1)-n1nc2c(NC(=O)c3ccc(N)cc3)nc3ccccc3n2c1=O

InChI Key: InChIKey=FBYKFERGBCFEJR-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50423870 (CHEMBL2024147) Show SMILES COc1ccc(cc1)-n1nc2c(NC(=O)c3ccc(N)cc3)nc3ccccc3n2c1=O Show InChI InChI=1S/C23H18N6O3/c1-32-17-12-10-16(11-13-17)29-23(31)28-19-5-3-2-4-18(19)25-20(21(28)27-29)26-22(30)14-6-8-15(24)9-7-14/h2-13H,24H2,1H3,(H,25,26,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a
University of Nottingham Curated by ChEMBL					Assay Description Antagonist activity at human adenosine A3 receptor expressed in forskolin-stimulated CHO cells assessed as inhibition of NECA-induced CRE-SPAP gene t...				J Med Chem 55: 1771-82 (2012) Article DOI: 10.1021/jm201722y BindingDB Entry DOI: 10.7270/Q2ST7R4K
					More data for this Ligand-Target Pair