BDBM50424328 CHEMBL2314500

SMILES: CN1CCCN(CC1)c1nc(N)nc2[nH]ccc12

InChI Key: InChIKey=SUCQRXUPCXTVSO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424328   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50424328 (CHEMBL2314500) Show SMILES CN1CCCN(CC1)c1nc(N)nc2[nH]ccc12 Show InChI InChI=1S/C12H18N6/c1-17-5-2-6-18(8-7-17)11-9-3-4-14-10(9)15-12(13)16-11/h3-4H,2,5-8H2,1H3,(H3,13,14,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Displacement of [3H]Histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai/o and Gbeta1gamma				Bioorg Med Chem Lett 23: 132-7 (2012) Article DOI: 10.1016/j.bmcl.2012.10.139 BindingDB Entry DOI: 10.7270/Q28P61TF
					More data for this Ligand-Target Pair