BDBM50424376 CHEMBL2314798

SMILES: COC[C@H](C)Oc1cc(\C=C\c2ccc(F)cc2)cc(c1)C(=O)Nc1ccn(C)n1

InChI Key: InChIKey=PCJDRDWQCZXOQF-APHBUQMISA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424376   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50424376 (CHEMBL2314798) Show SMILES COC[C@H](C)Oc1cc(\C=C\c2ccc(F)cc2)cc(c1)C(=O)Nc1ccn(C)n1 |r| Show InChI InChI=1S/C23H24FN3O3/c1-16(15-29-3)30-21-13-18(5-4-17-6-8-20(24)9-7-17)12-19(14-21)23(28)25-22-10-11-27(2)26-22/h4-14,16H,15H2,1-3H3,(H,25,26,28)/b5-4+/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	119	n/a	n/a	n/a	n/a
Yuhan Research Institute Curated by ChEMBL					Assay Description Induction of human pancreatic glucokinase activity at 5 mM glucose concentration				Bioorg Med Chem Lett 23: 537-42 (2012) Article DOI: 10.1016/j.bmcl.2012.11.018 BindingDB Entry DOI: 10.7270/Q2154JCQ
					More data for this Ligand-Target Pair