null

SMILES: COc1ccc(NC(=O)c2ccnc3ccccc23)c(n1)C(=O)NCC1CCC1

InChI Key: InChIKey=GHCQHKJDEOAEFX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50424465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50424465 (CHEMBL2316404) Show SMILES COc1ccc(NC(=O)c2ccnc3ccccc23)c(n1)C(=O)NCC1CCC1 Show InChI InChI=1S/C22H22N4O3/c1-29-19-10-9-18(20(26-19)22(28)24-13-14-5-4-6-14)25-21(27)16-11-12-23-17-8-3-2-7-15(16)17/h2-3,7-12,14H,4-6,13H2,1H3,(H,24,28)(H,25,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in HEK293S cell membranes after 1 hr by GTPgamma[35S] binding assay				J Med Chem 56: 220-40 (2013) Article DOI: 10.1021/jm301511h BindingDB Entry DOI: 10.7270/Q2057H7B
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50424465 (CHEMBL2316404) Show SMILES COc1ccc(NC(=O)c2ccnc3ccccc23)c(n1)C(=O)NCC1CCC1 Show InChI InChI=1S/C22H22N4O3/c1-29-19-10-9-18(20(26-19)22(28)24-13-14-5-4-6-14)25-21(27)16-11-12-23-17-8-3-2-7-15(16)17/h2-3,7-12,14H,4-6,13H2,1H3,(H,24,28)(H,25,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-CP55,940 from human CB1 receptor expressed in HEK293S cell membranes by scintillation counting analysis				J Med Chem 56: 220-40 (2013) Article DOI: 10.1021/jm301511h BindingDB Entry DOI: 10.7270/Q2057H7B
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50424465 (CHEMBL2316404) Show SMILES COc1ccc(NC(=O)c2ccnc3ccccc23)c(n1)C(=O)NCC1CCC1 Show InChI InChI=1S/C22H22N4O3/c1-29-19-10-9-18(20(26-19)22(28)24-13-14-5-4-6-14)25-21(27)16-11-12-23-17-8-3-2-7-15(16)17/h2-3,7-12,14H,4-6,13H2,1H3,(H,24,28)(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor expressed in Sf9 cell membranes by scintillation counting analysis				J Med Chem 56: 220-40 (2013) Article DOI: 10.1021/jm301511h BindingDB Entry DOI: 10.7270/Q2057H7B
					More data for this Ligand-Target Pair