BDBM50424551 CHEMBL2312520

SMILES: CC(C)OC(=O)N1C2CC3CC1CC(C2)N3c1ncnc(Oc2cccnc2C)c1C

InChI Key: InChIKey=ZBUTVWLKBMCCQB-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50424551 (CHEMBL2312520) Show SMILES CC(C)OC(=O)N1C2CC3CC1CC(C2)N3c1ncnc(Oc2cccnc2C)c1C |TLB:10:9:6.11.12:14,4:6:14:8.9.15,THB:10:11:14:8.9.15,15:9:6:12.13.14,15:13:6:8.10.9,16:15:6.11.12:14| Show InChI InChI=1S/C23H29N5O3/c1-13(2)30-23(29)28-18-8-16-9-19(28)11-17(10-18)27(16)21-14(3)22(26-12-25-21)31-20-6-5-7-24-15(20)4/h5-7,12-13,16-19H,8-11H2,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human GPR119 in HEK293FT cell membrane by radioligand binding assay				J Med Chem 56: 301-19 (2013) Article DOI: 10.1021/jm301626p BindingDB Entry DOI: 10.7270/Q2BG2Q91
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50424551 (CHEMBL2312520) Show SMILES CC(C)OC(=O)N1C2CC3CC1CC(C2)N3c1ncnc(Oc2cccnc2C)c1C |TLB:10:9:6.11.12:14,4:6:14:8.9.15,THB:10:11:14:8.9.15,15:9:6:12.13.14,15:13:6:8.10.9,16:15:6.11.12:14| Show InChI InChI=1S/C23H29N5O3/c1-13(2)30-23(29)28-18-8-16-9-19(28)11-17(10-18)27(16)21-14(3)22(26-12-25-21)31-20-6-5-7-24-15(20)4/h5-7,12-13,16-19H,8-11H2,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	559	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 in HEK293 cells assessed as cAMP accumulation after 30 mins by CRE-beta-lactamase reporter gene assay				J Med Chem 56: 301-19 (2013) Article DOI: 10.1021/jm301626p BindingDB Entry DOI: 10.7270/Q2BG2Q91
					More data for this Ligand-Target Pair