BDBM50425235 CHEMBL2315167

SMILES: CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(nc3)N3CCNCC3)c2n1

InChI Key: InChIKey=RYSDMBBJASPMTK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50425235 (CHEMBL2315167) Show SMILES CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(nc3)N3CCNCC3)c2n1 Show InChI InChI=1S/C19H27N9O/c1-2-3-6-22-18-25-16(20)15-17(26-18)28(19(29)24-15)12-13-4-5-14(23-11-13)27-9-7-21-8-10-27/h4-5,11,21H,2-3,6-10,12H2,1H3,(H,24,29)(H3,20,22,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma. Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells by NFkappaB SEAP reporter gene assay				Bioorg Med Chem Lett 23: 669-72 (2013) Article DOI: 10.1016/j.bmcl.2012.11.114 BindingDB Entry DOI: 10.7270/Q2B859DG
					More data for this Ligand-Target Pair