BDBM50425373 CHEMBL2316200

SMILES: CC(C)C[C@H](NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1)C(O)=O

InChI Key: InChIKey=YTQKMHHLJZGVMM-VWLOTQADSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50425373 (CHEMBL2316200) Show SMILES CC(C)C[C@H](NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1)C(O)=O |r| Show InChI InChI=1S/C28H26F2N2O4/c1-15(2)11-25(28(35)36)32-27(34)18-6-4-16-3-5-17-12-20(8-9-21(17)26(33)22(16)13-18)31-24-10-7-19(29)14-23(24)30/h4,6-10,12-15,25,31H,3,5,11H2,1-2H3,(H,32,34)(H,35,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
University of T£bingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) by ELISA				J Med Chem 56: 241-53 (2013) Article DOI: 10.1021/jm301539x BindingDB Entry DOI: 10.7270/Q2TB187B
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