BDBM50425823 CHEMBL2316901

SMILES: OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccccc1

InChI Key: InChIKey=BGKWXWITXXDDOF-UHFFFAOYSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50425823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM50425823 (CHEMBL2316901) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C17H10O4/c1-2-11-12-8-13(17(19)20)14(18)9-15(12)21-16(11)10-6-4-3-5-7-10/h1,3-9,18H,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of VHR (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis				J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X
					More data for this Ligand-Target Pair
Leukocyte common antigen (Homo sapiens (Human))	BDBM50425823 (CHEMBL2316901) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C17H10O4/c1-2-11-12-8-13(17(19)20)14(18)9-15(12)21-16(11)10-6-4-3-5-7-10/h1,3-9,18H,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of CD45 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis				J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase MEG2 (PTP-Meg2) (Homo sapiens (Human))	BDBM50425823 (CHEMBL2316901) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C17H10O4/c1-2-11-12-8-13(17(19)20)14(18)9-15(12)21-16(11)10-6-4-3-5-7-10/h1,3-9,18H,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis				J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM50425823 (CHEMBL2316901) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C17H10O4/c1-2-11-12-8-13(17(19)20)14(18)9-15(12)21-16(11)10-6-4-3-5-7-10/h1,3-9,18H,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of LYP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis				J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM50425823 (CHEMBL2316901) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C17H10O4/c1-2-11-12-8-13(17(19)20)14(18)9-15(12)21-16(11)10-6-4-3-5-7-10/h1,3-9,18H,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 294) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...				J Med Chem 56: 4990-5008 (2013) Article DOI: 10.1021/jm400248c BindingDB Entry DOI: 10.7270/Q2N017XW
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1C (Homo sapiens (Human))	BDBM50425823 (CHEMBL2316901) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C17H10O4/c1-2-11-12-8-13(17(19)20)14(18)9-15(12)21-16(11)10-6-4-3-5-7-10/h1,3-9,18H,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of SHP1 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis				J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50425823 (CHEMBL2316901) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C17H10O4/c1-2-11-12-8-13(17(19)20)14(18)9-15(12)21-16(11)10-6-4-3-5-7-10/h1,3-9,18H,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of TCPTP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis				J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50425823 (CHEMBL2316901) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C17H10O4/c1-2-11-12-8-13(17(19)20)14(18)9-15(12)21-16(11)10-6-4-3-5-7-10/h1,3-9,18H,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis				J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50425823 (CHEMBL2316901) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C17H10O4/c1-2-11-12-8-13(17(19)20)14(18)9-15(12)21-16(11)10-6-4-3-5-7-10/h1,3-9,18H,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of SHP2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis				J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X
					More data for this Ligand-Target Pair