BDBM50425858 CHEMBL2312338

SMILES: Oc1c(F)cc(cc1F)-n1cccc1C(=O)c1ccc(Br)cc1F

InChI Key: InChIKey=JDOHUKWVYXYFDH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (Rattus norvegicus)	BDBM50425858 (CHEMBL2312338) Show SMILES Oc1c(F)cc(cc1F)-n1cccc1C(=O)c1ccc(Br)cc1F Show InChI InChI=1S/C17H9BrF3NO2/c18-9-3-4-11(12(19)6-9)16(23)15-2-1-5-22(15)10-7-13(20)17(24)14(21)8-10/h1-8,24H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Aristotle University of Thessaloniki Curated by ChEMBL					Assay Description Inhibition of Fischer-344 rat kidney ALR1 using D,L-glyceraldehyde as substrate by spectrophotometry				Bioorg Med Chem 21: 869-73 (2013) Article DOI: 10.1016/j.bmc.2012.12.015 BindingDB Entry DOI: 10.7270/Q22N53KJ
					More data for this Ligand-Target Pair