BDBM50425866 CHEMBL2312657

SMILES: O[C@@H]1COC[C@H]1Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1Br

InChI Key: InChIKey=CYYFQJUQUMBOSB-VXGBXAGGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425866   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50425866 (CHEMBL2312657) Show SMILES O[C@@H]1COC[C@H]1Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1Br |r| Show InChI InChI=1S/C14H13BrCl2N4O2/c15-10-4-18-14(19-9-2-7(16)1-8(17)3-9)21-13(10)20-11-5-23-6-12(11)22/h1-4,11-12,22H,5-6H2,(H2,18,19,20,21)/t11-,12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATP				Bioorg Med Chem Lett 23: 1051-5 (2013) Article DOI: 10.1016/j.bmcl.2012.12.028 BindingDB Entry DOI: 10.7270/Q2XW4M38
					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50425866 (CHEMBL2312657) Show SMILES O[C@@H]1COC[C@H]1Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1Br |r| Show InChI InChI=1S/C14H13BrCl2N4O2/c15-10-4-18-14(19-9-2-7(16)1-8(17)3-9)21-13(10)20-11-5-23-6-12(11)22/h1-4,11-12,22H,5-6H2,(H2,18,19,20,21)/t11-,12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of P-selectin aggregation in platelet surface (unknown origin)				Bioorg Med Chem Lett 23: 1051-5 (2013) Article DOI: 10.1016/j.bmcl.2012.12.028 BindingDB Entry DOI: 10.7270/Q2XW4M38
					More data for this Ligand-Target Pair