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SMILES: CN(C)C(=S)N(C#N)c1nc(C)cc(C)n1

InChI Key: InChIKey=YODZEACMIBRQDA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426162   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin K


(Homo sapiens (Human))		BDBM50426162
PNG
(CHEMBL2316609)
Show SMILES CN(C)C(=S)N(C#N)c1nc(C)cc(C)n1
Show InChI InChI=1S/C10H13N5S/c1-7-5-8(2)13-9(12-7)15(6-11)10(16)14(3)4/h5H,1-4H3
PDB
MMDB

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n/an/a>3.00E+4n/an/an/an/an/an/a



MSD Animal Health Innovation GmbH

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...

J Med Chem 56: 1478-90 (2013)


Article DOI: 10.1021/jm3013932
BindingDB Entry DOI: 10.7270/Q2W09774
More data for this
Ligand-Target Pair