BDBM50426221 CHEMBL2311947

SMILES: [O-][N+](=O)c1c(NCc2ccc(F)cc2Cl)ccc2nonc12

InChI Key: InChIKey=GJLPBJAKALWNPH-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50426221 (CHEMBL2311947) Show SMILES [O-][N+](=O)c1c(NCc2ccc(F)cc2Cl)ccc2nonc12 Show InChI InChI=1S/C13H8ClFN4O3/c14-9-5-8(15)2-1-7(9)6-16-11-4-3-10-12(18-22-17-10)13(11)19(20)21/h1-5,16H,6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type PAS-B domain of HIF-2alpha (unknown origin) by isothermal calorimetry analysis				J Med Chem 56: 1739-47 (2013) Article DOI: 10.1021/jm301847z BindingDB Entry DOI: 10.7270/Q2BZ67CG
					More data for this Ligand-Target Pair