BDBM50426783 CHEMBL2322449

SMILES: CCc1nc2ccn(Cc3cccc(C)c3)c(=O)c2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=LUULXVDREBHUFH-NDEPHWFRSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50426783 (CHEMBL2322449) Show SMILES CCc1nc2ccn(Cc3cccc(C)c3)c(=O)c2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C32H29N7O/c1-3-29-33-27-15-16-38(19-21-8-6-7-20(2)17-21)32(40)30(27)39(29)28-14-12-23-18-22(11-13-25(23)28)24-9-4-5-10-26(24)31-34-36-37-35-31/h4-11,13,15-18,28H,3,12,14,19H2,1-2H3,(H,34,35,36,37)/t28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after				Bioorg Med Chem Lett 23: 767-72 (2013) Article DOI: 10.1016/j.bmcl.2012.11.088 BindingDB Entry DOI: 10.7270/Q2542PW7
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50426783 (CHEMBL2322449) Show SMILES CCc1nc2ccn(Cc3cccc(C)c3)c(=O)c2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C32H29N7O/c1-3-29-33-27-15-16-38(19-21-8-6-7-20(2)17-21)32(40)30(27)39(29)28-14-12-23-18-22(11-13-25(23)28)24-9-4-5-10-26(24)31-34-36-37-35-31/h4-11,13,15-18,28H,3,12,14,19H2,1-2H3,(H,34,35,36,37)/t28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	108	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assay				Bioorg Med Chem Lett 23: 767-72 (2013) Article DOI: 10.1016/j.bmcl.2012.11.088 BindingDB Entry DOI: 10.7270/Q2542PW7
					More data for this Ligand-Target Pair