BDBM50426784 CHEMBL2322448

SMILES: CCc1nc2ccn(Cc3cccc(F)c3)c(=O)c2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=JLNFWGWIKOBDNT-MHZLTWQESA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50426784 (CHEMBL2322448) Show SMILES CCc1nc2ccn(Cc3cccc(F)c3)c(=O)c2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C31H26FN7O/c1-2-28-33-26-14-15-38(18-19-6-5-7-22(32)16-19)31(40)29(26)39(28)27-13-11-21-17-20(10-12-24(21)27)23-8-3-4-9-25(23)30-34-36-37-35-30/h3-10,12,14-17,27H,2,11,13,18H2,1H3,(H,34,35,36,37)/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after				Bioorg Med Chem Lett 23: 767-72 (2013) Article DOI: 10.1016/j.bmcl.2012.11.088 BindingDB Entry DOI: 10.7270/Q2542PW7
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50426784 (CHEMBL2322448) Show SMILES CCc1nc2ccn(Cc3cccc(F)c3)c(=O)c2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C31H26FN7O/c1-2-28-33-26-14-15-38(18-19-6-5-7-22(32)16-19)31(40)29(26)39(28)27-13-11-21-17-20(10-12-24(21)27)23-8-3-4-9-25(23)30-34-36-37-35-30/h3-10,12,14-17,27H,2,11,13,18H2,1H3,(H,34,35,36,37)/t27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	159	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assay				Bioorg Med Chem Lett 23: 767-72 (2013) Article DOI: 10.1016/j.bmcl.2012.11.088 BindingDB Entry DOI: 10.7270/Q2542PW7
					More data for this Ligand-Target Pair