BDBM50427093 CHEMBL2322860

SMILES: COc1cc(ccc1Cl)N1CCN(CC1)C(=O)Cn1nc(c(I)c1C)C(F)(F)F

InChI Key: InChIKey=WXVCARJCVBSLBW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50427093 (CHEMBL2322860) Show SMILES COc1cc(ccc1Cl)N1CCN(CC1)C(=O)Cn1nc(c(I)c1C)C(F)(F)F Show InChI InChI=1S/C18H19ClF3IN4O2/c1-11-16(23)17(18(20,21)22)24-27(11)10-15(28)26-7-5-25(6-8-26)12-3-4-13(19)14(9-12)29-2/h3-4,9H,5-8,10H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-CCL3/MIP-1alpha from CCR1 in human THP1 cells				Bioorg Med Chem Lett 23: 1228-31 (2013) Article DOI: 10.1016/j.bmcl.2013.01.005 BindingDB Entry DOI: 10.7270/Q2NZ88Z2
					More data for this Ligand-Target Pair