BDBM50427118 CHEMBL2322891

SMILES: Cc1c(Cl)c(nn1CC(=O)N1CCN(CC1)c1ccc(Br)cc1)C(F)(F)F

InChI Key: InChIKey=HBCMVDIOORTSMM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50427118 (CHEMBL2322891) Show SMILES Cc1c(Cl)c(nn1CC(=O)N1CCN(CC1)c1ccc(Br)cc1)C(F)(F)F Show InChI InChI=1S/C17H17BrClF3N4O/c1-11-15(19)16(17(20,21)22)23-26(11)10-14(27)25-8-6-24(7-9-25)13-4-2-12(18)3-5-13/h2-5H,6-10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-CCL3/MIP-1alpha from CCR1 in human THP1 cells				Bioorg Med Chem Lett 23: 1228-31 (2013) Article DOI: 10.1016/j.bmcl.2013.01.005 BindingDB Entry DOI: 10.7270/Q2NZ88Z2
					More data for this Ligand-Target Pair