null

SMILES: CCCS(=O)(=O)N1CCN(CC1)C1(CNC(=O)c2c(OC)cc(cc2C(F)(F)F)C(F)(F)F)CCCCC1

InChI Key: InChIKey=DDZGMGTXMYWFBR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50427184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50427184 (CHEMBL2324479) Show SMILES CCCS(=O)(=O)N1CCN(CC1)C1(CNC(=O)c2c(OC)cc(cc2C(F)(F)F)C(F)(F)F)CCCCC1 Show InChI InChI=1S/C24H33F6N3O4S/c1-3-13-38(35,36)33-11-9-32(10-12-33)22(7-5-4-6-8-22)16-31-21(34)20-18(24(28,29)30)14-17(23(25,26)27)15-19(20)37-2/h14-15H,3-13,16H2,1-2H3,(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human GlyT2 expressed in HEK293 cells assessed as inhibition of [3H]glycine uptake by scintillation proximity assay				Bioorg Med Chem Lett 23: 1257-61 (2013) Article DOI: 10.1016/j.bmcl.2013.01.006 BindingDB Entry DOI: 10.7270/Q2WH2RB6
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50427184 (CHEMBL2324479) Show SMILES CCCS(=O)(=O)N1CCN(CC1)C1(CNC(=O)c2c(OC)cc(cc2C(F)(F)F)C(F)(F)F)CCCCC1 Show InChI InChI=1S/C24H33F6N3O4S/c1-3-13-38(35,36)33-11-9-32(10-12-33)22(7-5-4-6-8-22)16-31-21(34)20-18(24(28,29)30)14-17(23(25,26)27)15-19(20)37-2/h14-15H,3-13,16H2,1-2H3,(H,31,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of GlyT1a in human JAR cells assessed as inhibition of [3H]glycine uptake by scintillation proximity assay				Bioorg Med Chem Lett 23: 1257-61 (2013) Article DOI: 10.1016/j.bmcl.2013.01.006 BindingDB Entry DOI: 10.7270/Q2WH2RB6
					More data for this Ligand-Target Pair