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BDBM50427264 CHEMBL2325434

SMILES: CCc1ccc(cc1)C(CCCN)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=WODICWGGSGIADK-UHFFFAOYSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427264   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50427264
PNG
(CHEMBL2325434)
Show SMILES CCc1ccc(cc1)C(CCCN)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H27N/c1-2-20-14-16-23(17-15-20)24(18-9-19-25,21-10-5-3-6-11-21)22-12-7-4-8-13-22/h3-8,10-17H,2,9,18-19,25H2,1H3
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
9.70n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...


J Med Chem 56: 1878-93 (2013)


Article DOI: 10.1021/jm3014597
BindingDB Entry DOI: 10.7270/Q20866NN
More data for this
Ligand-Target Pair