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SMILES: Cc1ccc(c(F)c1)C(SCCN)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=IRTRVUMXVOKGFY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427269   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50427269
PNG
(CHEMBL2325405)
Show SMILES Cc1ccc(c(F)c1)C(SCCN)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H22FNS/c1-17-12-13-20(21(23)16-17)22(25-15-14-24,18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-13,16H,14-15,24H2,1H3
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Article
PubMed
 201n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...

J Med Chem 56: 1878-93 (2013)


Article DOI: 10.1021/jm3014597
BindingDB Entry DOI: 10.7270/Q20866NN
More data for this
Ligand-Target Pair