BDBM50427371 CHEMBL2326015

SMILES: Fc1ccc(nc1-c1n[nH]c2ncccc12)N1CCNCC1

InChI Key: InChIKey=AFICENYJQYURCA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50427371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50427371 (CHEMBL2326015) Show SMILES Fc1ccc(nc1-c1n[nH]c2ncccc12)N1CCNCC1 Show InChI InChI=1S/C15H15FN6/c16-11-3-4-12(22-8-6-17-7-9-22)19-14(11)13-10-2-1-5-18-15(10)21-20-13/h1-5,17H,6-9H2,(H,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL					Assay Description Inhibition of full-length recombinant PKC theta (unknown origin) using ERMRPRKRQGSVRRRV as substrate after 60 mins by scintillation counting analysis...				J Med Chem 56: 1799-810 (2013) Article DOI: 10.1021/jm301465a BindingDB Entry DOI: 10.7270/Q2M046R2
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50427371 (CHEMBL2326015) Show SMILES Fc1ccc(nc1-c1n[nH]c2ncccc12)N1CCNCC1 Show InChI InChI=1S/C15H15FN6/c16-11-3-4-12(22-8-6-17-7-9-22)19-14(11)13-10-2-1-5-18-15(10)21-20-13/h1-5,17H,6-9H2,(H,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	722	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL					Assay Description Inhibition of PKC delta (unknown origin) using ERMRPRKRQGSVRRRV as substrate after 15 mins by spectrophotometry in presence of ATP				J Med Chem 56: 1799-810 (2013) Article DOI: 10.1021/jm301465a BindingDB Entry DOI: 10.7270/Q2M046R2
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50427371 (CHEMBL2326015) Show SMILES Fc1ccc(nc1-c1n[nH]c2ncccc12)N1CCNCC1 Show InChI InChI=1S/C15H15FN6/c16-11-3-4-12(22-8-6-17-7-9-22)19-14(11)13-10-2-1-5-18-15(10)21-20-13/h1-5,17H,6-9H2,(H,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL					Assay Description Inhibition of PKC alpha (unknown origin) using RRRRRKGSFKRKA as substrate after 15 mins by spectrophotometry in presence of ATP				J Med Chem 56: 1799-810 (2013) Article DOI: 10.1021/jm301465a BindingDB Entry DOI: 10.7270/Q2M046R2
					More data for this Ligand-Target Pair