null

SMILES: O=C(CCc1nc2ccccc2n(CCc2ccccc2)c1=O)N1CCCCC1

InChI Key: InChIKey=HLHIBUVFWATTTK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50427448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase (Trypanosoma brucei)	BDBM50427448 (CHEMBL2326945) Show SMILES O=C(CCc1nc2ccccc2n(CCc2ccccc2)c1=O)N1CCCCC1 Show InChI InChI=1S/C24H27N3O2/c28-23(26-16-7-2-8-17-26)14-13-21-24(29)27(18-15-19-9-3-1-4-10-19)22-12-6-5-11-20(22)25-21/h1,3-6,9-12H,2,7-8,13-18H2	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei full length PDEB1 expressed in insect SF21 cells using cAMP as substrate by scintillation proximity assay				J Med Chem 56: 2087-96 (2013) Article DOI: 10.1021/jm3017877 BindingDB Entry DOI: 10.7270/Q2319X7M
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50427448 (CHEMBL2326945) Show SMILES O=C(CCc1nc2ccccc2n(CCc2ccccc2)c1=O)N1CCCCC1 Show InChI InChI=1S/C24H27N3O2/c28-23(26-16-7-2-8-17-26)14-13-21-24(29)27(18-15-19-9-3-1-4-10-19)22-12-6-5-11-20(22)25-21/h1,3-6,9-12H,2,7-8,13-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Inhibition of human full length PDE4B expressed in insect SF21 cells using cAMP as substrate by scintillation proximity assay				J Med Chem 56: 2087-96 (2013) Article DOI: 10.1021/jm3017877 BindingDB Entry DOI: 10.7270/Q2319X7M
					More data for this Ligand-Target Pair