BDBM50427517 CHEMBL2322265

SMILES: Cc1c(CCC(=O)Nc2ccc(N)cc2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12

InChI Key: InChIKey=KQSYGNACKVYJFK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B (NF-kB) (Homo sapiens (Human))	BDBM50427517 (CHEMBL2322265) Show SMILES Cc1c(CCC(=O)Nc2ccc(N)cc2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12 Show InChI InChI=1S/C26H26N2O4/c1-14-18(11-12-23(29)28-17-9-7-16(27)8-10-17)26(30)32-24-15(2)25-21(13-20(14)24)19-5-3-4-6-22(19)31-25/h7-10,13H,3-6,11-12,27H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+6	n/a	n/a	n/a	n/a
Universit£ degli Studi di Padova Curated by ChEMBL					Assay Description Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...				J Med Chem 56: 1830-42 (2013) Article DOI: 10.1021/jm3009647 BindingDB Entry DOI: 10.7270/Q2TH8P10
					More data for this Ligand-Target Pair