BDBM50427538 CHEMBL2322279

SMILES: Cc1c(CCC(=O)NC(Cc2ccccc2)C(O)=O)c(=O)oc2cc3oc4CCCCc4c3cc12

InChI Key: InChIKey=NOAJKRBLYPWHLX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B (NF-kB) (Homo sapiens (Human))	BDBM50427538 (CHEMBL2322279) Show SMILES Cc1c(CCC(=O)NC(Cc2ccccc2)C(O)=O)c(=O)oc2cc3oc4CCCCc4c3cc12 Show InChI InChI=1S/C28H27NO6/c1-16-18(11-12-26(30)29-22(27(31)32)13-17-7-3-2-4-8-17)28(33)35-24-15-25-21(14-20(16)24)19-9-5-6-10-23(19)34-25/h2-4,7-8,14-15,22H,5-6,9-13H2,1H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a
Universit£ degli Studi di Padova Curated by ChEMBL					Assay Description Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...				J Med Chem 56: 1830-42 (2013) Article DOI: 10.1021/jm3009647 BindingDB Entry DOI: 10.7270/Q2TH8P10
					More data for this Ligand-Target Pair