BDBM50427539 CHEMBL2322278

SMILES: Cc1c(CC(=O)Nc2ccc(cc2)C(O)=O)c(=O)oc2cc3oc4CCCCc4c3cc12

InChI Key: InChIKey=GWEYXJIVRBCQKT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B (NF-kB) (Homo sapiens (Human))	BDBM50427539 (CHEMBL2322278) Show SMILES Cc1c(CC(=O)Nc2ccc(cc2)C(O)=O)c(=O)oc2cc3oc4CCCCc4c3cc12 Show InChI InChI=1S/C25H21NO6/c1-13-17-10-19-16-4-2-3-5-20(16)31-22(19)12-21(17)32-25(30)18(13)11-23(27)26-15-8-6-14(7-9-15)24(28)29/h6-10,12H,2-5,11H2,1H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Padova Curated by ChEMBL					Assay Description Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...				J Med Chem 56: 1830-42 (2013) Article DOI: 10.1021/jm3009647 BindingDB Entry DOI: 10.7270/Q2TH8P10
					More data for this Ligand-Target Pair