BDBM50427783 CHEMBL2325172

SMILES: O=C(NCc1ccccn1)Nc1ccc2nnsc2c1

InChI Key: InChIKey=JMKLDYHWEXOMBB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 3 (Homo sapiens (Human))	BDBM50427783 (CHEMBL2325172) Show SMILES O=C(NCc1ccccn1)Nc1ccc2nnsc2c1 Show InChI InChI=1S/C13H11N5OS/c19-13(15-8-10-3-1-2-6-14-10)16-9-4-5-11-12(7-9)20-18-17-11/h1-7H,8H2,(H2,15,16,19)	PDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...				J Med Chem 56: 2110-24 (2013) Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ
					More data for this Ligand-Target Pair