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SMILES: Nc1nc2n(cnc2c(=O)[nH]1)C(COCP(O)(O)=O)COCP(O)(O)=O

InChI Key: InChIKey=HGFVDMDQWOKBNA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427807   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hypoxanthine-guanine phosphoribosyltransferase


(Homo sapiens (Human))		BDBM50427807
PNG
(CHEMBL2325755)
Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)C(COCP(O)(O)=O)COCP(O)(O)=O
Show InChI InChI=1S/C10H17N5O9P2/c11-10-13-8-7(9(16)14-10)12-3-15(8)6(1-23-4-25(17,18)19)2-24-5-26(20,21)22/h3,6H,1-2,4-5H2,(H2,17,18,19)(H2,20,21,22)(H3,11,13,14,16)
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 3.70E+4n/an/an/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal hexahistidine-tagged HGPRT

J Med Chem 56: 2513-26 (2013)


Article DOI: 10.1021/jm301893b
BindingDB Entry DOI: 10.7270/Q2MW2JGT
More data for this
Ligand-Target Pair