BDBM50427898 CHEMBL242857

SMILES: COc1ccc-2c(c1)C(=O)c1c-2n(CCCN)c(=O)c2ccccc12

InChI Key: InChIKey=ZXQWPYBSFPAGRZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50427898 (CHEMBL242857) Show SMILES COc1ccc-2c(c1)C(=O)c1c-2n(CCCN)c(=O)c2ccccc12 Show InChI InChI=1S/C20H18N2O3/c1-25-12-7-8-14-16(11-12)19(23)17-13-5-2-3-6-15(13)20(24)22(18(14)17)10-4-9-21/h2-3,5-8,11H,4,9-10,21H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.84E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assay				J Med Chem 56: 2581-605 (2013) Article DOI: 10.1021/jm400026k BindingDB Entry DOI: 10.7270/Q2G44RNG
					More data for this Ligand-Target Pair