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SMILES: O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1nc(cs1)-c1ccccc1

InChI Key: InChIKey=JEGLSFWNRZCXHI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50428021   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-serine O-palmitoleoyltransferase porcupine


(Mus musculus)		BDBM50428021
PNG
(CHEMBL2323238)
Show SMILES O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C23H18N4O2S3/c28-19(26-22-24-18(13-31-22)15-7-3-1-4-8-15)14-32-23-25-17-11-12-30-20(17)21(29)27(23)16-9-5-2-6-10-16/h1-10,13H,11-12,14H2,(H,24,26,28)
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Article
PubMed
n/an/an/an/a 350n/an/an/an/a



The University of Texas Southwestern Medical Center

Curated by ChEMBL


Assay Description
Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assay

J Med Chem 56: 2700-4 (2013)


Article DOI: 10.1021/jm400159c
BindingDB Entry DOI: 10.7270/Q2TD9ZP5
More data for this
Ligand-Target Pair