BDBM50428255 CHEMBL1231559

SMILES: OC(=O)c1ccc2ccccc2c1-c1c(ccc2ccccc12)C(O)=O

InChI Key: InChIKey=YDZNRNHKJQTGCG-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50428255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50428255 (CHEMBL1231559) Show SMILES OC(=O)c1ccc2ccccc2c1-c1c(ccc2ccccc12)C(O)=O |(-4.26,1.44,;-3.56,.84,;-3.56,-.7,;-1.59,1.44,;-1.59,2.98,;-.26,3.75,;1.07,2.98,;2.41,3.75,;3.74,2.98,;3.74,1.44,;2.41,.67,;1.07,1.44,;-.26,.67,;-.26,-.87,;-1.59,-1.64,;-1.59,-3.18,;-.26,-3.95,;1.07,-3.18,;2.41,-3.95,;3.74,-3.18,;3.74,-1.64,;2.41,-.87,;1.07,-1.64,;-2.93,-.87,;-4.26,-1.64,;-2.93,.67,)| Show InChI InChI=1S/C22H14O4/c23-21(24)17-11-9-13-5-1-3-7-15(13)19(17)20-16-8-4-2-6-14(16)10-12-18(20)22(25)26/h1-12H,(H,23,24)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Antagonist activity at WDR5 (unknown origin)				ACS Med Chem Lett 4: 353-7 (2013) Article DOI: 10.1021/ml300467n BindingDB Entry DOI: 10.7270/Q2C53N6F
					More data for this Ligand-Target Pair