BDBM50428279 CHEMBL2337901
SMILES: Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccc(cc2)-c2ccc(Nc3cc(c(N)c4C(=O)c5ccccc5C(=O)c34)S([O-])(=O)=O)cc2)cc1S([O-])(=O)=O
InChI Key: InChIKey=MCXHECMXNQTDIG-UHFFFAOYSA-L
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50428279 (CHEMBL2337901) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Soochow University Curated by ChEMBL | Assay Description Inhibition of c-Met (unknown origin) using Poly(Glu,Tyr) at 4:1 ratio as substrate preincubated with substrate prior to enzyme addition measured afte... | ACS Med Chem Lett 4: 408-13 (2013) Article DOI: 10.1021/ml4000047 BindingDB Entry DOI: 10.7270/Q23R0V7M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor (Homo sapiens (Human)) | BDBM50428279 (CHEMBL2337901) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a | n/a |
Soochow University Curated by ChEMBL | Assay Description Binding affinity to immobilized HGF (unknown origin) by surface plasmon resonance analysis | ACS Med Chem Lett 4: 408-13 (2013) Article DOI: 10.1021/ml4000047 BindingDB Entry DOI: 10.7270/Q23R0V7M | |||||||||||
More data for this Ligand-Target Pair |