null
SMILES: NS(=O)(=O)c1ccc(cc1)-n1nc(CO)cc1-c1cccnc1
InChI Key: InChIKey=OXDZTUCLLJDORR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM50428520 (CHEMBL2336632) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille Nord de France Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 9 preincubated for 10 mins by CO2 hydration stopped-flow assay | Bioorg Med Chem 21: 1451-64 (2013) Article DOI: 10.1016/j.bmc.2012.10.029 BindingDB Entry DOI: 10.7270/Q2ZS2XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50428520 (CHEMBL2336632) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille Nord de France Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 10 mins by CO2 hydration stopped-flow assay | Bioorg Med Chem 21: 1451-64 (2013) Article DOI: 10.1016/j.bmc.2012.10.029 BindingDB Entry DOI: 10.7270/Q2ZS2XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50428520 (CHEMBL2336632) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 87 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille Nord de France Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 preincubated for 10 mins by CO2 hydration stopped-flow assay | Bioorg Med Chem 21: 1451-64 (2013) Article DOI: 10.1016/j.bmc.2012.10.029 BindingDB Entry DOI: 10.7270/Q2ZS2XVC | |||||||||||
More data for this Ligand-Target Pair |