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SMILES: COc1ccc(cc1)-c1c[nH]c2c1C(=O)c1[nH]cc3CCN=C2c13

InChI Key: InChIKey=PRBNCMXEZHTISA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50428664   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))		BDBM50428664
PNG
(CHEMBL576344)
Show SMILES COc1ccc(cc1)-c1c[nH]c2c1C(=O)c1[nH]cc3CCN=C2c13 |t:23|
Show InChI InChI=1S/C19H15N3O2/c1-24-12-4-2-10(3-5-12)13-9-22-17-15(13)19(23)18-14-11(8-21-18)6-7-20-16(14)17/h2-5,8-9,21-22H,6-7H2,1H3
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Article
PubMed
n/an/a 7.10E+3n/an/an/an/an/an/a



University of Namur

Curated by ChEMBL


Assay Description
Inhibition of human recombinant IDO1 using L-Trp as substrate assessed as kynurenine level after 30 mins

Bioorg Med Chem Lett 23: 47-54 (2012)


Article DOI: 10.1016/j.bmcl.2012.11.036
BindingDB Entry DOI: 10.7270/Q2JM2C03
More data for this
Ligand-Target Pair