BDBM50428996 CHEMBL2333657

SMILES: Cc1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(Br)c1O

InChI Key: InChIKey=SAXRFUUWLACAMK-CNHKJKLMSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50428996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50428996 (CHEMBL2333657) Show SMILES Cc1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(Br)c1O Show InChI InChI=1S/C15H12Br2N2O3/c1-8-2-4-9(5-3-8)15(22)19-18-7-10-6-11(16)14(21)12(17)13(10)20/h2-7,20-21H,1H3,(H,19,22)/b18-7+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...				J Med Chem 56: 761-80 (2013) Article DOI: 10.1021/jm301032j BindingDB Entry DOI: 10.7270/Q2XP768M
					More data for this Ligand-Target Pair