BDBM50429003 CHEMBL2333650

SMILES: Oc1ccc(\C=N\NC(=O)c2ccc(cc2)-c2ccccc2)c(O)c1

InChI Key: InChIKey=IAWZHJKLBJQAIY-FYJGNVAPSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429003   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50429003 (CHEMBL2333650) Show SMILES Oc1ccc(\C=N\NC(=O)c2ccc(cc2)-c2ccccc2)c(O)c1 Show InChI InChI=1S/C20H16N2O3/c23-18-11-10-17(19(24)12-18)13-21-22-20(25)16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-13,23-24H,(H,22,25)/b21-13+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...				J Med Chem 56: 761-80 (2013) Article DOI: 10.1021/jm301032j BindingDB Entry DOI: 10.7270/Q2XP768M
					More data for this Ligand-Target Pair