BDBM50429006 CHEMBL2333668

SMILES: Oc1ccc(cc1-c1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(Br)c1O)C#N

InChI Key: InChIKey=CEIJCHISBRPNKT-KIBLKLHPSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50429006 (CHEMBL2333668) Show SMILES Oc1ccc(cc1-c1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(Br)c1O)C#N Show InChI InChI=1S/C21H13Br2N3O4/c22-16-8-14(19(28)18(23)20(16)29)10-25-26-21(30)13-4-2-12(3-5-13)15-7-11(9-24)1-6-17(15)27/h1-8,10,27-29H,(H,26,30)/b25-10+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...				J Med Chem 56: 761-80 (2013) Article DOI: 10.1021/jm301032j BindingDB Entry DOI: 10.7270/Q2XP768M
					More data for this Ligand-Target Pair