BDBM50429194 CHEMBL2338105

SMILES: COc1cc2CCN(Cc3ccc(o3)-c3ccc4ccccc4c3)Cc2cc1OC

InChI Key: InChIKey=NJQLMRHQZPCZQN-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50429194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-glycoprotein 1 (Homo sapiens (Human))	BDBM50429194 (CHEMBL2338105) Show SMILES COc1cc2CCN(Cc3ccc(o3)-c3ccc4ccccc4c3)Cc2cc1OC Show InChI InChI=1S/C26H25NO3/c1-28-25-14-20-11-12-27(16-22(20)15-26(25)29-2)17-23-9-10-24(30-23)21-8-7-18-5-3-4-6-19(18)13-21/h3-10,13-15H,11-12,16-17H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari ALDO MORO Curated by ChEMBL					Assay Description Activity at MDR1 (unknown origin) expressed in MDCK cells assessed as interference with calcein-AM efflux incubated for 30 mins prior to calcein-Am a...				Bioorg Med Chem 21: 1324-32 (2013) Article DOI: 10.1016/j.bmc.2012.12.021 BindingDB Entry DOI: 10.7270/Q2HH6MDJ
					More data for this Ligand-Target Pair
Multidrug resistance protein 1/Multidrug resistance associated protein 1 (Homo sapiens (Human))	BDBM50429194 (CHEMBL2338105) Show SMILES COc1cc2CCN(Cc3ccc(o3)-c3ccc4ccccc4c3)Cc2cc1OC Show InChI InChI=1S/C26H25NO3/c1-28-25-14-20-11-12-27(16-22(20)15-26(25)29-2)17-23-9-10-24(30-23)21-8-7-18-5-3-4-6-19(18)13-21/h3-10,13-15H,11-12,16-17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari ALDO MORO Curated by ChEMBL					Assay Description Activity at MRP1 (unknown origin) expressed in MDCK cells assessed as interference calcein-AM efflux incubated for 30 mins prior to calcein-Am additi...				Bioorg Med Chem 21: 1324-32 (2013) Article DOI: 10.1016/j.bmc.2012.12.021 BindingDB Entry DOI: 10.7270/Q2HH6MDJ
					More data for this Ligand-Target Pair