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SMILES: COc1ccc(CC(OC(=O)\C=C\c2ccc(cc2)-c2ccccc2)C(=O)NO)cc1OC

InChI Key: InChIKey=HSZLGWCHNPBVDM-RVDMUPIBSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429243   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interstitial collagenase


(Homo sapiens (Human))		BDBM50429243
PNG
(CHEMBL2333277)
Show SMILES COc1ccc(CC(OC(=O)\C=C\c2ccc(cc2)-c2ccccc2)C(=O)NO)cc1OC
Show InChI InChI=1S/C26H25NO6/c1-31-22-14-10-19(16-23(22)32-2)17-24(26(29)27-30)33-25(28)15-11-18-8-12-21(13-9-18)20-6-4-3-5-7-20/h3-16,24,30H,17H2,1-2H3,(H,27,29)/b15-11+
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MMDB

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Article
PubMed
n/an/a 5.50E+3n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP1 catalytic domain using Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Lys-(Nma)-NH2 as substrate preincubated with ...

Eur J Med Chem 62: 148-57 (2013)


Article DOI: 10.1016/j.ejmech.2012.09.047
BindingDB Entry DOI: 10.7270/Q2VQ341V
More data for this
Ligand-Target Pair