BDBM50429260 CHEMBL2333732
SMILES: Oc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccc(Cl)cc2)CC1
InChI Key: InChIKey=HBGSAORKQHKGPY-UHFFFAOYSA-N
Data: 7 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50429260 (CHEMBL2333732) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal de Goi£s Curated by ChEMBL | Assay Description Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation counting | Eur J Med Chem 62: 214-21 (2013) Article DOI: 10.1016/j.ejmech.2012.08.011 BindingDB Entry DOI: 10.7270/Q2QZ2CBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50429260 (CHEMBL2333732) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal de Goi£s Curated by ChEMBL | Assay Description Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation counting | Eur J Med Chem 62: 214-21 (2013) Article DOI: 10.1016/j.ejmech.2012.08.011 BindingDB Entry DOI: 10.7270/Q2QZ2CBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50429260 (CHEMBL2333732) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal de Goi£s Curated by ChEMBL | Assay Description Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation counting | Eur J Med Chem 62: 214-21 (2013) Article DOI: 10.1016/j.ejmech.2012.08.011 BindingDB Entry DOI: 10.7270/Q2QZ2CBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50429260 (CHEMBL2333732) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal de Goi£s Curated by ChEMBL | Assay Description Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation counting | Eur J Med Chem 62: 214-21 (2013) Article DOI: 10.1016/j.ejmech.2012.08.011 BindingDB Entry DOI: 10.7270/Q2QZ2CBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Rattus norvegicus (rat)) | BDBM50429260 (CHEMBL2333732) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal de Goi£s Curated by ChEMBL | Assay Description Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation counting | Eur J Med Chem 62: 214-21 (2013) Article DOI: 10.1016/j.ejmech.2012.08.011 BindingDB Entry DOI: 10.7270/Q2QZ2CBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50429260 (CHEMBL2333732) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal de Goi£s Curated by ChEMBL | Assay Description Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation counting | Eur J Med Chem 62: 214-21 (2013) Article DOI: 10.1016/j.ejmech.2012.08.011 BindingDB Entry DOI: 10.7270/Q2QZ2CBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50429260 (CHEMBL2333732) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal de Goi£s Curated by ChEMBL | Assay Description Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation counting | Eur J Med Chem 62: 214-21 (2013) Article DOI: 10.1016/j.ejmech.2012.08.011 BindingDB Entry DOI: 10.7270/Q2QZ2CBK | |||||||||||
More data for this Ligand-Target Pair |