BDBM50429340 CHEMBL2334913

SMILES: CS(=O)(=O)c1ccc(cc1)C(=C/c1ccc(cc1)C(F)(F)F)\C(O)=O

InChI Key: InChIKey=GDISTPKCSVDBOT-XNTDXEJSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) (Homo sapiens (Human))	BDBM50429340 (CHEMBL2334913) Show SMILES CS(=O)(=O)c1ccc(cc1)C(=C/c1ccc(cc1)C(F)(F)F)\C(O)=O Show InChI InChI=1S/C17H13F3O4S/c1-25(23,24)14-8-4-12(5-9-14)15(16(21)22)10-11-2-6-13(7-3-11)17(18,19)20/h2-10H,1H3,(H,21,22)/b15-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of recombinant AKR1C3 (unknown origin) assessed as decrease in oxidation of 1-acenaphthenol substrate by spectrophotometric analysis				Eur J Med Chem 62: 89-97 (2013) Article DOI: 10.1016/j.ejmech.2012.12.045 BindingDB Entry DOI: 10.7270/Q2BR8TH0
					More data for this Ligand-Target Pair