BDBM50429396 CHEMBL2336761

SMILES: COc1cc2nc(OC3CCN(CC3)C(=O)OC(C)(C)C)nc(Nc3ccc(cc3)S(C)(=O)=O)c2cc1OC

InChI Key: InChIKey=QYOSKYNGFOIKLO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50429396 (CHEMBL2336761) Show SMILES COc1cc2nc(OC3CCN(CC3)C(=O)OC(C)(C)C)nc(Nc3ccc(cc3)S(C)(=O)=O)c2cc1OC Show InChI InChI=1S/C27H34N4O7S/c1-27(2,3)38-26(32)31-13-11-18(12-14-31)37-25-29-21-16-23(36-5)22(35-4)15-20(21)24(30-25)28-17-7-9-19(10-8-17)39(6,33)34/h7-10,15-16,18H,11-14H2,1-6H3,(H,28,29,30)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Kangwon National University Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 60 mins				Bioorg Med Chem 21: 1349-56 (2013) Article DOI: 10.1016/j.bmc.2012.12.013 BindingDB Entry DOI: 10.7270/Q2ZG6TKZ
					More data for this Ligand-Target Pair