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SMILES: COc1cccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)c1

InChI Key: InChIKey=SSOPBCAOUYATLR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429509   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Danio rerio)		BDBM50429509
PNG
(CHEMBL2332841)
Show SMILES COc1cccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)c1
Show InChI InChI=1S/C19H17N7O2/c1-28-15-4-2-3-14(9-15)25-19(27)24-13-7-5-12(6-8-13)23-17-16-10-22-26-18(16)21-11-20-17/h2-11H,1H3,(H2,24,25,27)(H2,20,21,22,23,26)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...

J Med Chem 56: 1641-55 (2013)


Article DOI: 10.1021/jm301537p
BindingDB Entry DOI: 10.7270/Q29S1SC5
More data for this
Ligand-Target Pair