BDBM50429628 CHEMBL2334575

SMILES: Cc1nc2cc(C)ccn2c1-c1ccnc(N)n1

InChI Key: InChIKey=OQODWFCIKXTEHB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429628   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 14 (Homo sapiens (Human))	BDBM50429628 (CHEMBL2334575) Show SMILES Cc1nc2cc(C)ccn2c1-c1ccnc(N)n1 Show InChI InChI=1S/C13H13N5/c1-8-4-6-18-11(7-8)16-9(2)12(18)10-3-5-15-13(14)17-10/h3-7H,1-2H3,(H2,14,15,17)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assay				Bioorg Med Chem Lett 23: 1238-44 (2013) Article DOI: 10.1016/j.bmcl.2013.01.012 BindingDB Entry DOI: 10.7270/Q2J967RQ
					More data for this Ligand-Target Pair