null

SMILES: Cc1cc2c(cc1-n1c(N)nc3cc(ccc13)C(O)=O)C(C)(C)CCC2(C)C

InChI Key: InChIKey=WWFKXOHNVWKPRM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50429864 (CHEMBL2332886) Show SMILES Cc1cc2c(cc1-n1c(N)nc3cc(ccc13)C(O)=O)C(C)(C)CCC2(C)C |(24.03,-22.65,;22.68,-21.9,;21.37,-22.7,;20.02,-21.95,;19.98,-20.42,;21.31,-19.62,;22.65,-20.36,;23.97,-19.57,;25.39,-20.16,;25.73,-21.66,;26.39,-19,;25.6,-17.68,;26.04,-16.21,;24.99,-15.09,;23.49,-15.43,;23.05,-16.91,;24.1,-18.03,;25.44,-13.61,;26.94,-13.26,;24.38,-12.48,;18.66,-19.65,;17.6,-18.53,;19.6,-18.48,;17.32,-20.47,;17.35,-22.01,;18.68,-22.77,;19.73,-23.89,;17.73,-23.95,)| Show InChI InChI=1S/C23H27N3O2/c1-13-10-15-16(23(4,5)9-8-22(15,2)3)12-19(13)26-18-7-6-14(20(27)28)11-17(18)25-21(26)24/h6-7,10-12H,8-9H2,1-5H3,(H2,24,25)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	155	n/a	n/a	n/a	n/a
Okayama University Graduate School of Medicine Curated by ChEMBL					Assay Description Partial agonist activity at RXRalpha (unknown origin) expressed in COS1 cells after 18 hrs by luciferase reporter gene assay				J Med Chem 56: 1865-77 (2013) Article DOI: 10.1021/jm400033f BindingDB Entry DOI: 10.7270/Q2348MR8
					More data for this Ligand-Target Pair