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SMILES: Cc1cc2c(cc1-n1ccc3cc(ccc13)C(O)=O)C(C)(C)CCC2(C)C

InChI Key: InChIKey=VQOPKHQLHMCHMC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429865   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))		BDBM50429865
PNG
(CHEMBL2332890)
Show SMILES Cc1cc2c(cc1-n1ccc3cc(ccc13)C(O)=O)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H27NO2/c1-15-12-18-19(24(4,5)10-9-23(18,2)3)14-21(15)25-11-8-16-13-17(22(26)27)6-7-20(16)25/h6-8,11-14H,9-10H2,1-5H3,(H,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 83n/an/an/an/a



Okayama University Graduate School of Medicine

Curated by ChEMBL


Assay Description
Partial agonist activity at RXRalpha (unknown origin) expressed in COS1 cells after 18 hrs by luciferase reporter gene assay

J Med Chem 56: 1865-77 (2013)


Article DOI: 10.1021/jm400033f
BindingDB Entry DOI: 10.7270/Q2348MR8
More data for this
Ligand-Target Pair