null
SMILES: CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCOS(O)(=O)=O)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RNA-binding protein FXR1 (Human) | BDBM504302 (3α,7α,11β,23-tetrahydroxy-6α-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RNA-binding protein FXR1 (Human) | BDBM504302 (3α,7α,11β,23-tetrahydroxy-6α-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
FMR1 autosomal homolog 1 (Dog) | BDBM504302 (3α,7α,11β,23-tetrahydroxy-6α-e...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RNA-binding protein FXR1 (Mouse) | BDBM504302 (3α,7α,11β,23-tetrahydroxy-6α-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 250 | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RNA-binding protein FXR1 (Rat) | BDBM504302 (3α,7α,11β,23-tetrahydroxy-6α-e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RNA-binding protein FXR1 (Human) | BDBM504302 (3α,7α,11β,23-tetrahydroxy-6α-e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a |
TBA | Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W | |||||||||||
More data for this Ligand-Target Pair |