BDBM50430202 CHEMBL2332447
SMILES: CC1=Nc2cc(nn2[C@@H](C1c1ncnn1-c1cccc(C)n1)c1ccc(Cl)c(Cl)c1)C(F)(F)F
InChI Key: InChIKey=VVVYILYYYZPQDU-GFOWMXPYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human)) | BDBM50430202 (CHEMBL2332447) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 211 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Antagonist activity at human Kv1.5 expressed in mouse L929 cells assessed as inhibition of delayed rectifier repolarization current by patch clamp as... | Bioorg Med Chem Lett 23: 1743-7 (2013) Article DOI: 10.1016/j.bmcl.2013.01.064 BindingDB Entry DOI: 10.7270/Q2QN685H | |||||||||||
More data for this Ligand-Target Pair |