BDBM50430221 CHEMBL2331985

SMILES: CCCn1ncnc1C1[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C

InChI Key: InChIKey=FLSQQRJZMWZPHA-ZYMOGRSISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50430221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50430221 (CHEMBL2331985) Show SMILES CCCn1ncnc1C1[C@@H](c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C |r,c:26| Show InChI InChI=1S/C18H18Cl2N6/c1-3-8-25-18(21-10-23-25)16-11(2)24-15-6-7-22-26(15)17(16)12-4-5-13(19)14(20)9-12/h4-7,9-10,16-17H,3,8H2,1-2H3/t16?,17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Antagonist activity at human Kv1.5 expressed in mouse L929 cells assessed as inhibition of delayed rectifier repolarization current by patch clamp as...				Bioorg Med Chem Lett 23: 1743-7 (2013) Article DOI: 10.1016/j.bmcl.2013.01.064 BindingDB Entry DOI: 10.7270/Q2QN685H
					More data for this Ligand-Target Pair