BDBM50430364 CHEMBL2333912

SMILES: N[C@H](Cc1ccc(F)c(F)c1)c1nc2ccc(cc2c(=O)[nH]1)-c1cn[nH]c1

InChI Key: InChIKey=XIABLTGVFHRZRR-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50430364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50430364 (CHEMBL2333912) Show SMILES N[C@H](Cc1ccc(F)c(F)c1)c1nc2ccc(cc2c(=O)[nH]1)-c1cn[nH]c1 |r| Show InChI InChI=1S/C19H15F2N5O/c20-14-3-1-10(5-15(14)21)6-16(22)18-25-17-4-2-11(12-8-23-24-9-12)7-13(17)19(27)26-18/h1-5,7-9,16H,6,22H2,(H,23,24)(H,25,26,27)/t16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant 6-His-tagged ROCK2 expressed in baculovirus-infected Sf9 cells using LCB-AKRRRLSSLRA-NH2 as substrate after 25 mins b...				Bioorg Med Chem Lett 23: 1592-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.109 BindingDB Entry DOI: 10.7270/Q2TD9ZQM
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